Derpetology
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Monday, March 30, 2026
fluorouracil and its cousins (fluoropyrimidine)
Years ago, when I started this project, I wondered about pyrimidine antivirals.
It turns out such things do exist. Fluorouracil and its cousins are used as chemotherapy drugs, antifungals, and antivirals. I wonder what effects a dimer version of fluorouracil would have.
chlorhexidine, proguanil, and metformin comparison
The chain with five nitrogen atoms is intriguing feature of all three. One could almost say that chlorhexidine (a disinfectant) is made from two proguanil molecules connected with a carbon chain.
abacavir, cladribine, and fludarabine comparison
The first is a medication for HIV, and the other two are chemotherapy drugs. The nitrogen double ring (purine-like) is an intriguing feature of all three.
cocaine, scopolamine, and hyoscine butyl bromide comparison
The nitrogen ring is very similar on all three. I wonder what effects cocaine butyl bromide would have. What would happen if cocaine was made to be more like scopolamine or vice-versa?
ivermectin, nystatin, amphotericin b, paclitaxel, and rifapentine comparison
Their molecular weights are similar, and they all have a large central ring. The antifungals nystatin and amphotericin b only differ in minor ways.
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