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Thursday, April 9, 2026

4-aminosalicylic acid, isoniazid, and ethionamide comparison

All are used to treat tuberculosis. All have a keto (thioketone in one case) group, an amino group, and a 6-sided ring. I suspect there are other potential tuberculosis drugs that have the same functional groups. 






chronology of common anesthetics

Once the first two were discovered and analyzed, there was a gradual push to combine them and make different asymmetrical halogenated ethers. The last one is a somewhat asymmetrical ester salt. I suspect another anesthetic could be made by chlorinating and/or fluorinating diethyl ether.  

19th century 




20th century







melphalan, ifosfamide, bendamustine, and cyclophosphamide comparison

All are chemotherapy drugs, and all have two chloroethyl chains coming off nitrogen atoms. I suspect there are similar drugs yet to be synthesized.