Total Pageviews

Search This Blog

Thursday, April 16, 2026

Wednesday, April 15, 2026

aciclovir, ganciclovir, valganciclovir, and valaciclovir comparison

All are antivirals. What would be the effect of replacing an alcohol group with a fluorine or a chlorine atom? 




chlorambucil - a melphalan cousin

It is a chemotherapy drug and has structural similarities with several others. 

Tuesday, April 14, 2026

sofosbuvir - another fluorouracil cousin

It is used to treat hepatitis C.

cephalosporins, beta lactams, and fluorouracil

Below are the general structural formulas for cephalosporin and beta lactam antibiotics. What would be the effect of substituting the sulfur ring with fluorouracil?








Monday, April 13, 2026

norepinephrine, methyldopa, dopamine, and epinephrine comparison

Norepinephrine increases blood pressure and methyldopa reduces it. But why? Could new blood pressure medicines be made by substituting a carboxylic acid group for an amino group?